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Product Name | LRRK2-IN-1 |
Description | Potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2). Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC50 values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2. Purity 98%. MW (observed): 570.09 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
Gene, Accession, CAS # | CAS: 1234480-84-2 |
Catalog # | 4273/10 |
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Order / More Info | LRRK2-IN-1 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25009464, 25118928, 25500533 |
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