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| Product Name | LSN 2463359 |
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| Description | Potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). Has no activity at mGlu1-4, mGlu8 and GABAB receptors. Reverses methylazoxymethanol acetate (MAM)-induced deficits in reversal learning memory and normalizes SDZ 220-581 and RO 63-1908 -induced alterations in instrumental responses in rat models. Promotes wakefulness in vivo. Brain penetrant and orally active. Purity 99%. MW (observed): 265.31 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(1-Methylethyl)-5-[2-(4-pyridinyl)ethynyl]-2-pyridinecarboxamide |
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| Gene, Accession, CAS # | CAS: 1401031-52-4 |
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| Catalog # | 5275/10 |
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| Order / More Info | LSN 2463359 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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