产品详情 |
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Product Name | dBRD9 |
Description | PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide (Cat. No. 6302). Potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). Does not degrade BRD4 or BRD7 at concentrations up to 5 μM. Displays antiproliferative effects in human AML cell lines. Purity 98%. MW (observed): 856.75 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2-6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide dihydrochloride |
Gene, Accession, CAS # | n/a |
Catalog # | 6606/5 |
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Order / More Info | dBRD9 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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