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| Product Name | 10-DEBC hydrochloride |
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| Description | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells. Purity 99%. MW (observed): 381.34 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride. Akt Inhibitor X |
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| Gene, Accession, CAS # | CAS: 925681-41-0 |
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| Catalog # | 2558/50 |
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| Price | |
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| Order / More Info | 10-DEBC hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21945811, 22278715, 24243084 |
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