产品详情 |
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Product Name | TC-S 7009 |
Description | High affinity and selective HIF-2α inhibitor (Kd = 81 nM). Binds to the HIF-2α PAS-B domain; disrupts HIF-2α-ARNT heterodimerization. Exhibits >60-fold selectivity for HIF-2α over HIF-1α. Decreases HIF-2α DNA-binding and attenuates expression of HIF-2α target genes in vitro. Purity 99%. MW (observed): 308.65 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine |
Gene, Accession, CAS # | CAS: 1422955-31-4 |
Catalog # | 5243/25 |
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Order / More Info | TC-S 7009 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 23434853 |
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