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| Product Name | TC-S 7006 |
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| Description | Potent and selective Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM). Selective for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. Inhibits LPS-induced TNF-α secretion from monocytes and attenuates acute myeloid leukemia (AML) cell proliferation in vitro. Also reduces cytolytic activity of human CD8+ cytotoxic T lymphocytes. Cell permeable. Purity 99%. MW (observed): 404.83 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile |
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| Gene, Accession, CAS # | CAS: 871307-18-5 |
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| Catalog # | 5240/10 |
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| Price | |
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| Order / More Info | TC-S 7006 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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