| 产品详情 |
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| Product Name | BIX 01294 |
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| Description | GLP and G9a histone lysine methyltransferase inhibitor (IC50 values are 0.7 and 1.7 μM respectively) that displays no activity at other histone methyltransferases up to 37 μM. Modulates H3K9me2 levels in mammalian cells and potentiates induction of pluripotent stem cells from somatic cells in vitro. Also inhibits H3K36 methylation by oncoproteins NSD1, NSD2 and NSD3 (IC50 values are 40 - 112 μM). Purity 98%. MW (observed): 600.02 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
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| Gene, Accession, CAS # | CAS: 1392399-03-9 |
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| Catalog # | 3364/10 |
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| Price | |
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| Order / More Info | BIX 01294 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21209933 |
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| 产品资料 |
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