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Product Name | BMS 509744 |
Description | Potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitor (IC50 = 19 nM). Displays 200-fold selectivity over Tec family kinases and 55-fold selectivity over other kinases tested. Reduces HIV infection of primary CD4+ T cells and attenuates the establishment of HIV infection in vitro. Reduces T cell proliferation and IL-2 production in vitro. Reduces lung inflammation in a mouse model of ovalbumin-induced allergy/asthma. Purity 97%. MW (observed): 623.83 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[5-[[5-[(4-Acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2,2-trimethylpropyl)amino]methyl]benzamide |
Gene, Accession, CAS # | CAS: 439575-02-7 |
Catalog # | 5009/10 |
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Order / More Info | BMS 509744 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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