产品详情 |
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Product Name | Borrelidin |
Description | Antibiotic and antiangiogenic. Selectively inhibits threonyl-tRNA synthetase (ThrRS). Exhibits antiangiogenic activity in a mouse model of tumor angiogenesis. Induces apoptosis in capillary tube-forming endothelial cells; disrupts capillary tubes and inhibits their formation (IC50 = 0.8 nM in rat aorta). Induces the unfolded protein response (UPR) and apoptosis in oral cancer cells. Purity 98%. MW (observed): 489.64 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid |
Gene, Accession, CAS # | CAS: 7184-60-3 |
Catalog # | 4706/1 |
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Order / More Info | Borrelidin from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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