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| Product Name | Nexinhib20 |
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| Description | Rab27 inhibitor (IC50 = 330 nM); inhibits Rab27a-JFC1 binding. Selectively inhibits neutrophil exocytosis, with no significant effect on other important innate immune responses including phagocytosis. Suppresses extracellular production of superoxide anion and cytochrome b plasma membrane expression. Also inhibits upregulation of adhesion molecules CD11b and CD66b. Displays in vivo anti-inflammatory activity. Purity 98%. MW (observed): 300.31 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4,4-Dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-penten-3-one |
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| Gene, Accession, CAS # | CAS: 331949-35-0 |
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| Catalog # | 6089/5 |
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| Price | |
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| Order / More Info | Nexinhib20 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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