| 产品详情 |
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| Product Name | NF 1819 |
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| Description | Potent and selective irreversible MAGL inhibitor (IC50 values are 0.25 and 7.4 nM at rMAGL and hMAGL, respectively). Exhibits 389-fold selectivity over hFAAH and exhibits minimal binding at CB receptors (IC50 > 10 μM). Alleviates symptoms in a MS in vivo model. Exhibits analgesic effects in an acute inflammatory pain model in vivo. Ameliorates neuropathic hypersensitivity induced by oxaliplatin (Cat. No. 2623). Displays high membrane permeability and brain penetrant. Purity 98%. MW (observed): 463.46 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone |
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| Gene, Accession, CAS # | CAS: 1881244-28-5 |
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| Catalog # | 5956/10 |
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| Price | |
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| Order / More Info | NF 1819 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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