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Product Name | NG 25 |
Description | TGF-β-activated kinase (TAK1) inhibitor (IC50 = 149 nM). Also inhibits LYN, MAP4K2 and Abl kinase activity (IC50 values are 12.9, 21.7 and 75.2 nM, respectively). Suppresses CpG A and CpG B-stimulated secretion of IFN-α and TLR7/8 agonist CL097-stimulated secretion of IFN-β in Gen 2.2 leukemia cells in vitro. Purity 98%. MW (observed): 537.58 |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide |
Gene, Accession, CAS # | CAS: 1315355-93-1 |
Catalog # | 5429/5 |
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Order / More Info | NG 25 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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