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| Product Name | NH 125 |
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| Description | Eukaryotic elongation factor 2 (eEF-2) kinase (CaMK III) inhibitor (IC50 = 60 nM) that displays 125-fold, > 1300-fold and > 1500-fold selectivity over PKC, PKA and CaMK II respectively. Decreases the viability of a variety of cancer cell lines (IC50 values are 0.7 - 4.8 μM) and blocks G1/S cell cycle progression. Shown to induce eEF-2 phosphorylation in cancer cells. Also an effective antibacterial agent; inhibits histidine protein kinase in vitro (IC50 = 6.6 μM) and in vivo. MW (observed): 524.56. |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-Hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium iodide |
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| Gene, Accession, CAS # | CAS: 278603-08-0 |
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| Catalog # | 3439/10 |
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| Price | |
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| Order / More Info | NH 125 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23182879, 23336064, 26039584, 28429770 |
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