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| Product Name | BX 471 |
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| Description | Potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. Inhibits MIP-α/CCL3-induced intracellular Ca2+ mobilization. Orally active; effectively reduces disease severity in a rat model of multiple sclerosis. Decreases renal fibrosis in a mouse model of obstructive nephropathy. Purity 98%. MW (observed): 434.89 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine |
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| Gene, Accession, CAS # | CAS: 217645-70-0 |
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| Catalog # | 3496/10 |
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| Price | |
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| Order / More Info | BX 471 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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