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Product Name | 680C91 |
Description | Potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) (Ki = 51 nM). Exhibits no activity against indoleamine 2,3-dioxygenase, monoamine oxidase A and B, 5-HT uptake or 5-HT1A, 1D, 2A and 2C receptors. Produces large increases in brain tryptophan and serotonin in vitro and in vivo in the rat. Purity 98%. MW (observed): 238.26 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole |
Gene, Accession, CAS # | CAS: 163239-22-3 |
Catalog # | 4392/25 |
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Order / More Info | 680C91 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 26363006, 27114543 |
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