产品详情 |
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Product Name | AS 605240 |
Description | Potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8 nM). Displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive. Purity 98%. MW (observed): 257.27 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione |
Gene, Accession, CAS # | CAS: 648450-29-7 |
Catalog # | 3578/10 |
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Order / More Info | AS 605240 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22402981, 22434859 |
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