| 产品详情 |
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| Product Name | ASP 3026 |
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| Description | Potent anaplastic lymphoma kinase (ALK) inhibitor (IC50 = 3.5 nM). Also inhibits Ack and ROS1 activity (IC50 values are 5.8 and 8.9 nM respectively). Attenuates proliferation, and induces apoptosis of NPM-ALK+ T cell anaplastic large-cell lymphoma (ALCL) cells in vitro. Suppresses tumor growth of NPM-ALK+ ALCL cell xenografts in mice. Causes tumor shrinkage in hEML4-ALK transgenic mice. Orally available. Purity 99%. MW (observed): 580.74 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine |
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| Gene, Accession, CAS # | CAS: 1097917-15-1 |
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| Catalog # | 5310/10 |
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| Price | |
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| Order / More Info | ASP 3026 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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