| 产品详情 |
| Edit |   |
|---|
| Product Name | AT 101 |
|---|
| Description | R-(-)-enantiomer of gossypol (Cat. No. 1964). Mimics the BH3 domains of Bcl-2, Bcl-XL and Mcl-1. Disrupts heterodimerization of Bcl-2 with proapoptotic family members. Induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. Delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo. Purity 98%. MW (observed): 518.56 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde |
|---|
| Gene, Accession, CAS # | CAS: 90141-22-3 |
|---|
| Catalog # | 3367/50 |
|---|
| Price | |
|---|
| Order / More Info | AT 101 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 27203692 |
|---|
| 产品资料 |
|
|