产品详情 |
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Product Name | Auranofin |
Description | Inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Thought to induce the mitochondrial permeability transition via inhibition of mitochondrial TrxR. Also exhibits anti-inflammatory and immunosuppressive activities; inhibits 5-lipoxygenase at high concentrations and stimulates LTA hydrolase at low concentrations. MW (observed): 678.48. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-Thio-β-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetraacetate |
Gene, Accession, CAS # | CAS: 34031-32-8 |
Catalog # | 4600/10 |
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Order / More Info | Auranofin from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 26187466 |
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