| 产品详情 |
| Edit |   |
|---|
| Product Name | FM19G11 |
|---|
| Description | Hypoxia inducible factor (HIF) α-subunit inhibitor (IC50 = 80 nM in hypoxia induced luciferase assay). Inhibits transcriptional activity of HIFα isoforms. Directly regulates expression and inhibits transcriptional activity of pluripotency markers (Sox2 and Oct4) in rodent and human stem cells under hypoxic conditions, driving differentiation. Improves locomotion after severe spinal cord injury in mice, alone or in combination with transplantation of ependymal stem cells of the spinal cord. Also inhibits O6-methylguanine DNA methyltransferase (MGMT) via HIF1α pathway, under normal and hypoxic conditions in glioblastoma cell lines. Purity 98%. MW (observed): 463.4 |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoate |
|---|
| Gene, Accession, CAS # | CAS: 329932-55-0 |
|---|
| Catalog # | 6653/5 |
|---|
| Price | |
|---|
| Order / More Info | FM19G11 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|