| 产品详情 |
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| Product Name | FTIDC |
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| Description | Potent and selective mGlu1 receptor negative allosteric modulator (IC50 values are 5.8 and 6200 nM for mGlu1 and mGlu5 respectively). Also acts as an mGlu1 receptor inverse agonist (IC50 = 7 nM) in the absence of ligand. Exhibits no effect at group II/III mGlu receptors. Inhibits L-glutamate-induced increases in intracellular calcium in mGlu1-expressing CHO cells. Inhibits nociceptive behavior, and exhibits anxiolytic and antipsychotic effects in vivo. Orally active. Purity 98%. MW (observed): 358.41 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[1-(2-Fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-3,6-dihydro-N-methyl-N-(1-methylethyl)-1(2H)-pyridinecarboxamide |
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| Gene, Accession, CAS # | CAS: 873551-53-2 |
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| Catalog # | 5000/10 |
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| Price | |
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| Order / More Info | FTIDC from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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