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Product Name | FTI 277 |
Description | Prodrug form of FTI 276 (Cat. No. 2406) that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 μM respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines. Purity 95%. MW (observed): 561.64 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt |
Gene, Accession, CAS # | CAS: 1217447-06-7 |
Catalog # | 2407/1 |
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Order / More Info | FTI 277 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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