产品详情 |
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Product Name | FTY 720 |
Description | S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ~3 nM for S1P3). Immunosuppresant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable. Purity 99%. MW (observed): 343.93 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride. Fingolimod, Gilenya |
Gene, Accession, CAS # | CAS: 162359-56-0 |
Catalog # | 6176/10 |
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Order / More Info | FTY 720 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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