产品详情 |
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Product Name | Org 48762-0 |
Description | Selective p38α and β kinase inhibitor (EC50 = 0.1 μM for p38α). Selective for p38α/β over a panel of 48 other human kinases. Inhibits LPS-induced TNFα release from PBMCs. Also inhibits cytokine release in an LPS-induced endotoxemia model in mice. Orally bioavailable. Purity 98%. MW (observed): 398.41 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4,6-Bis(4-fluorophenyl)-2-methyl-5-(4-pyridinyl)-2H-pyrazolo[3,4-b]pyridine |
Gene, Accession, CAS # | CAS: 755753-89-0 |
Catalog # | 6014/10 |
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Order / More Info | Org 48762-0 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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