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| Product Name | P 22077 |
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| Description | Inhibitor of ubiquitin-specific protease (USP) 7 (EC50 = 8.6 μM); also inhibits the closely related deubiquitinase (DUB) USP47. Demonstrates downstream inhibition of HDM2 and claspin in vitro. Inhibits USP7-mediated p53 deubiquitination. Blocks deubiquitination of Tip60 (KAT5) histone lysine acetyltransferase. Purity 99%. MW (observed): 315.32 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[5-[(2,4-Difluorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
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| Gene, Accession, CAS # | CAS: 1247819-59-5 |
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| Catalog # | 4485/10 |
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| Price | |
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| Order / More Info | P 22077 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25605328, 26950370 |
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