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Product Name | E 64 |
Description | Potent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1 nM for cathepsin K, L and S respectively. Also inhibits papain, calpain, cathepsin B and cathepsin H. Has no effect on serine proteases. Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites. Also inhibits autophagy-associated lysosomal degradation in vitro. Purity 98%. MW (observed): 357.41 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (2S,3S)-3-[[[(1S)-1-[[[4-(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid |
Gene, Accession, CAS # | CAS: 66701-25-5 |
Catalog # | 5208/10 |
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Order / More Info | E 64 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 26242194 |
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