| 产品详情 |
| Edit |   |
|---|
| Product Name | Ro 106-9920 |
|---|
| Description | Inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Purity 99%. MW (observed): 245.26 |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 6-(Phenylsulfinyl)tetrazolo[1,5-b]pyridazine |
|---|
| Gene, Accession, CAS # | CAS: 62645-28-7 |
|---|
| Catalog # | 1778/10 |
|---|
| Price | |
|---|
| Order / More Info | Ro 106-9920 from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 23536315, 25914608, 26714634 |
|---|
| 产品资料 |
|
|