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Product Name | Ro 15-4513 |
Description | High affinity benzodiazepine ligand. Ki values are 3.1 and 5.3 nM for diazepam-insensitive (DI) and diazepam-sensitive (DS) benzodiazepine receptors respectively. Acts as partial inverse agonist at recombinant DS α1-, α2-, α3- and α5-GABAA receptors. Displays partial agonism at DI α4- and α6-GABAA receptors. Antagonizes several behavioral and neurochemical effects of ethanol. Proconvulsant and anxiogenic. Purity 98%. MW (observed): 326.31 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 8-Azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid ethyl ester |
Gene, Accession, CAS # | CAS: 91917-65-6 |
Catalog # | 1997/10 |
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Order / More Info | Ro 15-4513 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22732440, 26612620 |
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