产品名称 Ro 5-3335 from TOCRIS BIOSCIENCE
产品货号 4694/10
产品价格 现货询价,电话:010-67529703
产品规格 10 mg
产品品牌 TOCRIS BIOSCIENCE
产品概述
产品详情
Edit&nbsp
Product NameRo 5-3335
DescriptionCore binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins (IC50 = 1.1 μM). Represses RUNX1/CBFβ-dependent transactivation in reporter assays and inhibits transcriptional regulation by RUNX1 and CBFβ. Reduces leukemia burden in a mouse model. Attenuates RUNX1-dependent hematopoiesis in zebrafish embryos. Also a Tat antagonist; inhibits HIV-1 replication in vitro. Purity 98%. MW (observed): 259.69
Size10 mg
Concentrationn/a
Applicationsn/a
Other Names7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one. CBFβ-Runx1 inhibitor II
Gene, Accession, CAS #CAS: 30195-30-3
Catalog #4694/10
Price
Order / More InfoRo 5-3335 from TOCRIS BIOSCIENCE
Product Specific ReferencesPubMed: 27573239
产品资料