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Product Name | Ro 31-8220 mesylate |
Description | Protein kinase C inhibitor, with activity at other protein kinases (IC50 values are 33, 3, 8, 15 and 38 nM for PKCα, MAPKAP-K1b, MSK1, GSK3β and S6K1 respectively). Activates JNK and glycogen synthase, and inhibits MAPK and ERK2, in rat adipocytes and L6 myotubes. Also inhibits voltage-dependent Na+ channels in the micromolar range. Purity 97%. MW (observed): 553.65 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl carbamimidothioic acid ester mesylate. Bisindolylmaleimide IX |
Gene, Accession, CAS # | CAS: 138489-18-6 |
Catalog # | 2002/10 |
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Order / More Info | Ro 31-8220 mesylate from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24265838, 25225290, 25596492, 26370265, 27320041, 30543664 |
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