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| Product Name | Roscovitine |
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| Description | Cyclin-dependent kinase (cdk) inhibitor. Displays sub-micromolar inhibition of cdk1, cdk2, cdk5, cdk7 and cdk9 (reported IC50 values range from 0.16 - 0.28 μM for cdk5 to 0.8 μM for cdk7). Selective for cdks over a wide range of related kinases including ERK1 and ERK2. Arrests L1210 cells in G1 phase. Inhibits phosphorylation of vimentin in vivo. Antimitotic. Purity 98%. MW (observed): 354.45 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
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| Gene, Accession, CAS # | CAS: 186692-46-6 |
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| Catalog # | 1332/10 |
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| Order / More Info | Roscovitine from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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