产品详情 |
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Product Name | HPI 1 |
Description | Hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4 and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation). Also inhibits Hh pathway activation in SmoM2-LIGHT cells (IC50 = 2.5 μM); inhibits the proliferation of cerebellar granule neuron precursors expressing SmoM2. Does not inhibit Wnt signaling. Purity 95%. MW (observed): 463.52 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylic acid 2-methoxyethyl ester |
Gene, Accession, CAS # | CAS: 599150-20-6 |
Catalog # | 3839/50 |
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Order / More Info | HPI 1 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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