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Product Name | HTH 01-015 |
Description | Potent and selective NUAK1 inhibitor (IC50 = 100 nM). Exhibits no significant inhibition against a panel of 139 kinases, including ten AMPK family members. Inhibits NUAK1-mediated MYPT1 phosphorylation. Also inhibits cell proliferation in U2OS cells in vitro, to a similar extent as NUAK1 knockdown models. Purity 98%. MW (observed): 468.55 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5,13-Dihydro-4,5,13-trimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one |
Gene, Accession, CAS # | CAS: 1613724-42-7 |
Catalog # | 5622/50 |
Price | |
Order / More Info | HTH 01-015 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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