| 产品详情 |
| Edit |   |
|---|
| Product Name | Clofarabine |
|---|
| Description | Deoxycytidine kinase (dCK) substrate. Phosphorylated to form clofarabine triphosphate, which competes with dATP for DNA polymerase-α and -ε and potently inhibits ribonucleotide reductase (IC50 = 65 nM). Induces apoptosis by directly altering mitochondrial transmembrane potential. Demonstrates growth inhibition and cytotoxic activity in a variety of leukemias and solid tumors. Purity 99%. MW (observed): 303.68 |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine |
|---|
| Gene, Accession, CAS # | CAS: 123318-82-1 |
|---|
| Catalog # | 2600/25 |
|---|
| Price | |
|---|
| Order / More Info | Clofarabine from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | PubMed: 22488775 |
|---|
| 产品资料 |
|
|