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| Product Name | Clozapine N-oxide |
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| Description | Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine. Water soluble salt also available. This product contains 1 molar equivalent of ethanol.. Purity 99%. MW (observed): 342.82 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
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| Gene, Accession, CAS # | CAS: 34233-69-7 |
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| Catalog # | 4936/10 |
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| Order / More Info | Clozapine N-oxide from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 26758850, 26974347, 27866960, 27939976, 28106041, 28538173, 28584117, 28602353, 28658323, 28684275, 29356147, 29410218, 30301899, 30833673 |
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