产品名称 CM 11 from TOCRIS BIOSCIENCE
产品货号 6416/5
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 TOCRIS BIOSCIENCE
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Product NameCM 11
DescriptionHomo-PROTAC for self-degradation of the long form of VHL, pVHL30 (DC50 < 100 nM). Composed of two VHL ligands joined by a linker. Exhibits > 1000-fold increased cellular activity compared to the parent VHL ligand, VH 032. Dimerizes pVHL30 with high avidity in vitro. Induced potent and rapid self-degradation of VHL in cell lines in a highly isoform dependent fashion. Negative control CMP 98 (Cat. No. 6417) also available. PROTACs are bi-functional small molecules that harness the ubiquitin/proteasome system (UPS) to selectively and catalytically remove target proteins from cells.. Purity 98%. MW (observed): 1179.46
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesN1,N20-bis((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,6,9,12,15,18-hexaoxaicosanediamide
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Catalog #6416/5
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Order / More InfoCM 11 from TOCRIS BIOSCIENCE
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