| 产品详情 |
| Edit |   |
|---|
| Product Name | PS 1145 dihydrochloride |
|---|
| Description | Selective IκB kinase (IKK) inhibitor (IC50 = 100 nM). Has no effect on PKA, PKC and CKII activity. Inhibits IκB-α phosphorylation and NFκB activation in HeLa cells. Inhibits NFκB-mediated proinflammatory gene expression in human airway epithelial cells. Enhances TNF-α-induced apoptosis in a multiple myeloma cell line. Attenuates LPS-induced TNF-α production in vivo. Orally active. Purity 98%. MW (observed): 395.67 |
|---|
| Size | 50 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide dihydrochloride |
|---|
| Gene, Accession, CAS # | CAS: 1049743-58-9 |
|---|
| Catalog # | 4569/50 |
|---|
| Price | |
|---|
| Order / More Info | PS 1145 dihydrochloride from TOCRIS BIOSCIENCE
|
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|