| 产品详情 |
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| Product Name | IKK 16 |
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| Description | Selective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). Inhibits TNF-α-stimulated IκB degradation and expression of adhesion molecules E-selectin, ICAM and VCAM (IC50 values are 1.0, 0.5, 0.3 and 0.3 μM respectively). Inhibits LPS-induced TNF-α release in vivo and neutrophil extravasion in thioglycollate-induced peritonitis. Purity 98%. MW (observed): 520.09 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride |
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| Gene, Accession, CAS # | CAS: 1186195-62-9 |
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| Catalog # | 2539/10 |
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| Order / More Info | IKK 16 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23571017, 23593196, 24928390, 26101953, 26331681, 26871947, 27820799 |
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