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Product Name | Imatinib mesylate |
Description | Potent and selective v-Abl tyrosine kinase inhibitor (IC50 = 38 nM). Also inhibits PDGFR and c-kit. Exhibits selectivity for v-Abl over a panel of other tyrosine and serine/threonine protein kinases. Selectively inhibits PDGF-stimulated growth of v-abl-transformed PB-3 cells and v-sis-transformed BALB/c 3T3 cells in vitro. Exhibits antitumor effects in mice bearing AMuLV or BABL/c 3T3 v-sis cells. Purity 98%. MW (observed): 589.71 |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate. Gleevec, CGP 57148B |
Gene, Accession, CAS # | CAS: 220127-57-1 |
Catalog # | 5906/100 |
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Order / More Info | Imatinib mesylate from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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