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Product Name | Indirubin-3'-oxime |
Description | Inhibitor of GSK-3β (IC50 = 190 nM) and cyclin dependent kinases (cdks; IC50 values are 0.05, 0.18 and 0.25-0.5 βM for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3β-mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation. Purity 99%. MW (observed): 277.28 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one. Indirubin-3'-monoxime |
Gene, Accession, CAS # | CAS: 160807-49-8 |
Catalog # | 1813/50 |
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Order / More Info | Indirubin-3'-oxime from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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