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| Product Name | SB 225002 |
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| Description | Potent and selective CXCR2 chemokine receptor antagonist (IC50 = 22 nM) that displays > 150-fold selectivity over CXCR1 receptors. Causes inhibition of IL-8 and GROα-mediated calcium mobilization in HL60 cells (IC50 values are 8 and 10 nM respectively). Prevents IL-8-induced neutrophil chemotaxis in vitro and sequestration in vivo. Inhibits HIV replication in lymphocytes and macrophages. Purity 99%. MW (observed): 352.14 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(2-Bromophenyl)-N'-(2-hydroxy-4-nitrophenyl)urea |
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| Gene, Accession, CAS # | CAS: 182498-32-4 |
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| Catalog # | 2725/50 |
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| Price | |
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| Order / More Info | SB 225002 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 20639353, 21383500, 21980263, 23283553, 23897983, 25712213, 25734337, 26414070, 27188501, 30175527 |
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