产品详情 |
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Product Name | SB 525334 |
Description | Selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Inhibits TGF-β1-induced smad2/3 nuclear localization and TGF-βRI-induced mRNA expression in kidney cells. Attenuates bleomycin-induced pulmonary fibrosis. Purity 97%. MW (observed): 343.42 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-[2-(1,1-Dimethylethyl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-4-yl]quinoxaline |
Gene, Accession, CAS # | CAS: 356559-20-1 |
Catalog # | 3211/10 |
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Order / More Info | SB 525334 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22675171, 23563587, 24158985, 25407459, 25946135, 26247610, 29700311 |
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