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| Product Name | SB 590885 |
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| Description | Potent B-Raf inhibitor (Kd = 0.3 nM). Selective for B-Raf against 46 other kinases (Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-RafV600E. Purity 98%. MW (observed): 453.54 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-[2-[4-[2-(Dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime |
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| Gene, Accession, CAS # | CAS: 405554-55-4 |
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| Catalog # | 2650/10 |
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| Price | |
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| Order / More Info | SB 590885 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23303345, 24112705, 25896324 |
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| 产品资料 |
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