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Product Name | SB 674042 |
Description | Potent and selective non-peptide orexin OX1 receptor antagonist (Kd = 3.76 nM). Exhibits 100-fold selectivity for OX1 over OX2 receptors. Has no effect at serotonergic, dopaminergic, adrenergic or purinergic receptors. Inhibits orexin 1-induced Ca2+ mobilization in CHO-DG44 cells stably transfected with the OX1 receptor. MW (observed): 448.51. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | [5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone |
Gene, Accession, CAS # | CAS: 483313-22-0 |
Catalog # | 4673/10 |
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Order / More Info | SB 674042 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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