产品详情 |
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Product Name | SBE 13 hydrochloride |
Description | Selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μM for PLK1, PLK3 and PLK2 respectively). Exhibits no effect on Aurora kinase A activity. Binds and stabilizes the inactive form of PLK1. Delays cell cycle progression, reduces cell proliferation and induces apoptosis in a range of human cancer cell lines. Transiently arrests cells cycle at G0/G1 in primary cells. Purity 99%. MW (observed): 479.4 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-[[4-[(6-Chloro-3-pyridinyl)methoxy]-3-methoxyphenyl]methyl]-3,4-dimethoxybenzeneethanamine hydrochloride |
Gene, Accession, CAS # | CAS: 1052532-15-6 |
Catalog # | 4292/50 |
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Order / More Info | SBE 13 hydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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