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| Product Name | Varenicline tartrate |
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| Description | Orally active, subtype-selective partial agonist at α4β2 nicotinic receptors (Ki values are 0.06, 240, 322 and 3540 nM for α4β2, α3β4, α7, α1βγδ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo. Also potently activates PSAM4-5-HT3 and PSAM4-GlyR chimeric ion channels (EC50 values are 4 and 1.6 nM, respectively). Purity 99%. MW (observed): 361.37 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate |
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| Gene, Accession, CAS # | CAS: 375815-87-5 |
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| Catalog # | 3754/10 |
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| Order / More Info | Varenicline tartrate from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 23638015, 25440006, 25648658, 30872534 |
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