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| Product Name | VAS 2870 |
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| Description | NADPH oxidase (Nox) inhibitor. Inhibits PMA-stimulated oxidative burst in HL-60 cells (IC50 = 2 μM). Inhibits oxidized-LDL-mediated, but not basal, ROS production in HUVECs in vitro. Also inhibits PDGF-mediated Nox activation and ROS formation in vascular smooth muscle cells (VSMCs) and abolishes PDGF-dependent migration of VSMCs, while having no effect on proliferation. Enhances TGF-β-induced apoptosis of liver tumor cells. Purity 98%. MW (observed): 360.39 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine |
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| Gene, Accession, CAS # | CAS: 722456-31-7 |
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| Catalog # | 6654/5 |
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| Order / More Info | VAS 2870 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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