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| Product Name | VE 821 |
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| Description | High affinity and selective ATP-competitive ATR inhibitor (Ki = 13 nM). Exhibits >75-fold selectivity for ATR over related kinases mTOR, DNA-PK, PI 3-Kγ and PIKKs (Ki values are >1, 2.2, 3.9 and 16 μM, respectively) and a panel of other kinases. Induces cell death in colon cancer cell lines in vitro and sensitizes tumor cells to treatment with DNA damaging anticancer agents. Purity 98%. MW (observed): 368.41 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Amino-6-[4-(methlsulfonyl)phenyl)-N-phenyl-2-pyrazinecarboxamide |
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| Gene, Accession, CAS # | CAS: 1232410-49-9 |
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| Catalog # | 6160/25 |
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| Order / More Info | VE 821 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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