| 产品详情 |
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| Product Name | VO-OHpic |
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| Description | Potent inhibitor of PTEN (phosphatase and tensin homolog) (IC50 = 35 nM). Displays selectivity for PTEN over cysteine-based phosphatases such as SopB, MTM, PTPβ and SAC (IC50 values are 588 nM, 4.03, 57.5 and >10 μM respectively). Increases PIP2 and PIP3 levels; also increases Akt translocation in NIH/3T3 fibroblasts. Blocks the immunosuppressant activity of IDO-activated Tregs. Promotes antitumor inflammatory response in combination with immunotherapy and enhances anticancer chemotherapy in tumor-bearing mice. Purity 98%. MW (observed): 361.16 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (OC-6-45)-Aqua(3-hydroxy-2-pyridinecarboxylato-κ-N1,κO2)[3-(hydroxy-κO)-2-pyridinecarboxylato(2-)-κO2]oxovanadate(1-),hydrogen |
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| Gene, Accession, CAS # | CAS: 675848-25-6 |
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| Catalog # | 3591/10 |
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| Price | |
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| Order / More Info | VO-OHpic from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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