产品名称 (+/-)-AMG 487 from TOCRIS BIOSCIENCE
产品货号 4487/50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 TOCRIS BIOSCIENCE
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Product Name(+/-)-AMG 487
DescriptionAntagonist of CXCR3; inhibits binding of 125I-IP-10 and 125I-ITAC to CXCR3 (IC50 values are 8.0 and 8.2 nM respectively). Inhibits CXCR3-mediated cell migration by the chemokines IP-10, ITAC and MiG in vitro (IC50 values are 8, 15 and 36 nM respectively). Also shown to inhibit lung metastasis in a mouse model of metastatic breast cancer. This product is racemic. . Purity 98%. MW (observed): 603.59
Size50 mg
Concentrationn/a
Applicationsn/a
Other NamesN-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(3-pyridinylmethyl)-4-(trifluoromethoxy)benzeneacetamide
Gene, Accession, CAS #CAS: 947536-03-0
Catalog #4487/50
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Product Specific ReferencesPubMed: 28986561, 30359318
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